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Category: Health professionals

Health professionals

Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

Familial chylomicronemia syndrome is a rare genetic disorder that is caused by loss of lipoprotein lipase activity and characterized by chylomicronemia and recurrent episodes of pancreatitis. There are no effective therapies. In an open-label study of three patients with this syndrome, antisense-mediated inhibition of hepatic APOC3 mRNA with volanesorsen led to decreased plasma apolipoprotein C-III and triglyceride levels.

Source: NEJM

Health professionals

Does diet quality or nutrient quantity contribute more to health?

Different lines of investigation suggest that “dietary quality” rather than “nutrient quantity” is a more reliable index for healthy nutrition. Any meaningful dietary intervention ought to extend far beyond the current focus on nutrient quantity and include the myriad qualitative aspects of food and food combinations, which would affect health and disease states.
Source:The Journal of Clinical Investigation

Health professionals

Higher circulating and tissue levels of Linoleic Acid associated with lower risk of major cardiovascular events

A recent study found that higher levels of circulating Linoleic Acid (LA) were significantly associated with lower risks of total cardiovascular disease (CVD), cardiovascular mortality, and ischemic stroke. Arachidonic Acid (AA) levels were not associated with higher risk of cardiovascular outcomes. In fact, comparing extreme quintiles, higher levels were associated with lower risk of total CVD. 

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